2RIQ
Crystal Structure of the Third Zinc-binding domain of human PARP-1
Summary for 2RIQ
Entry DOI | 10.2210/pdb2riq/pdb |
Descriptor | Poly [ADP-ribose] polymerase 1, ZINC ION, ETHANOL, ... (5 entities in total) |
Functional Keywords | zn-binding domain, zn ribbon, zn finger, adp-ribosylation, dna damage, dna repair, dna-binding, glycosyltransferase, metal-binding, nad, nucleus, phosphorylation, transferase, zinc-finger |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P09874 |
Total number of polymer chains | 1 |
Total formula weight | 18781.06 |
Authors | Pascal, J.M.,Langelier, M.F.,Servent, K.M. (deposition date: 2007-10-12, release date: 2008-01-08, Last modification date: 2024-02-21) |
Primary citation | Langelier, M.F.,Servent, K.M.,Rogers, E.E.,Pascal, J.M. A Third Zinc-binding Domain of Human Poly(ADP-ribose) Polymerase-1 Coordinates DNA-dependent Enzyme Activation. J.Biol.Chem., 283:4105-4114, 2008 Cited by PubMed: 18055453DOI: 10.1074/jbc.M708558200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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