2RIQ
Crystal Structure of the Third Zinc-binding domain of human PARP-1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Poly [ADP-ribose] polymerase 1 | polymer | 160 | 18393.3 | 1 | UniProt (P09874) Pfam (PF21728) Pfam (PF08063) In PDB | Homo sapiens (human) | PARP-1, ADPRT, NAD+, ADP-ribosyltransferase 1, Poly[ADP-ribose] synthetase 1 |
2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
3 | A | ETHANOL | non-polymer | 46.1 | 1 | Chemie (EOH) | |||
4 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
5 | water | water | 18.0 | 171 | Chemie (HOH) |
Sequence modifications
A: 216 - 366 (UniProt: P09874)
PDB | External Database | Details |
---|---|---|
Met 215 | - | initiating methionine |
Leu 367 | - | expression tag |
Glu 368 | - | expression tag |
His 369 | - | expression tag |
His 370 | - | expression tag |
His 371 | - | expression tag |
His 372 | - | expression tag |
His 373 | - | expression tag |
His 374 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 18393.3 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 387.8 | |
All* | Total formula weight | 18781.1 |