2PZG
Minimal human CFTR first nucleotide binding domain as a monomer
Summary for 2PZG
Entry DOI | 10.2210/pdb2pzg/pdb |
Related | 1L2T 1Q12 1R0Z 1R10 1XEF 1XMI 1XMJ 2BB0 2BBS 2BBT 2HYD 2IXE 2PZE 2PZF |
Descriptor | Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | nbd, abc transporter, cftr, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 55471.50 |
Authors | Atwell, S.,Conners, K.,Emtage, S.,Gheyi, T.,Glenn, N.R.,Hendle, J.,Lewis, H.A.,Lu, F.,Rodgers, L.A.,Romero, R.,Sauder, J.M.,Smith, D.,Tien, H.,Wasserman, S.R.,Zhao, X. (deposition date: 2007-05-18, release date: 2007-10-09, Last modification date: 2023-08-30) |
Primary citation | Atwell, S.,Brouillette, C.G.,Conners, K.,Emtage, S.,Gheyi, T.,Guggino, W.B.,Hendle, J.,Hunt, J.F.,Lewis, H.A.,Lu, F.,Protasevich, I.I.,Rodgers, L.A.,Romero, R.,Wasserman, S.R.,Weber, P.C.,Wetmore, D.,Zhang, F.F.,Zhao, X. Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant. Protein Eng.Des.Sel., 23:375-384, 2010 Cited by PubMed: 20150177DOI: 10.1093/protein/gzq004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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