2ODY

Thrombin-bound boophilin displays a functional and accessible reactive-site loop

Summary for 2ODY

• Entry DOI: 10.2210/pdb2ody/pdb
• Descriptor: Prothrombin (EC 3.4.21.5), Boophilin, PHOSPHATE ION, ... (7 entities in total)
• Functional Keywords: kunitz-type thrombin inhibitor, blood clotting-blood clotting inhibitor complex, blood clotting/blood clotting inhibitor
• Biological source: Rhipicephalus microplus (southern cattle tick); More
• Total number of polymer chains: 6
• Total formula weight: 99666.96

Authors

Macedo-Ribeiro, S.,Fuentes-Prior, P.,Pereira, P.J.B. (deposition date: 2006-12-27, release date: 2008-01-22, Last modification date: 2023-08-30)

• Primary citation: Macedo-Ribeiro, S.,Almeida, C.,Calisto, B.M.,Friedrich, T.,Mentele, R.,Sturzebecher, J.,Fuentes-Prior, P.,Pereira, P.J.; Isolation, cloning and structural characterisation of boophilin, a multifunctional kunitz-type proteinase inhibitor from the cattle tick.; Plos One, 3:e1624-e1624, 2008; PubMed: 18286181; DOI: 10.1371/journal.pone.0001624

Experimental method

X-RAY DIFFRACTION (2.35 Å)