2O8H
Crystal structure of the catalytic domain of rat phosphodiesterase 10A
Summary for 2O8H
| Entry DOI | 10.2210/pdb2o8h/pdb |
| Descriptor | Phosphodiesterase-10A, ZINC ION, MAGNESIUM ION, ... (5 entities in total) |
| Functional Keywords | phosphodiesterase 10a; zn-binding site, hydrolase |
| Biological source | Rattus norvegicus (Norway rat) |
| Cellular location | Cytoplasm : Q9QYJ6 |
| Total number of polymer chains | 1 |
| Total formula weight | 42235.01 |
| Authors | Pandit, J.,Marr, E.S. (deposition date: 2006-12-12, release date: 2007-01-09, Last modification date: 2024-04-03) |
| Primary citation | Chappie, T.A.,Humphrey, J.M.,Allen, M.P.,Estep, K.G.,Fox, C.B.,Lebel, L.A.,Liras, S.,Marr, E.S.,Menniti, F.S.,Pandit, J.,Schmidt, C.J.,Tu, M.,Williams, R.D.,Yang, F.V. Discovery of a series of 6,7-dimethoxy-4-pyrrolidylquinazoline PDE10A inhibitors J.Med.Chem., 50:182-185, 2007 Cited by PubMed: 17228859DOI: 10.1021/jm060653b PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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