2NRY
Crystal structure of IRAK-4
Summary for 2NRY
Entry DOI | 10.2210/pdb2nry/pdb |
Related | 2NRU |
Descriptor | interleukin-1 receptor-associated kinase 4, STAUROSPORINE (3 entities in total) |
Functional Keywords | kinase, inhibitor, staurosporine, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 139858.04 |
Authors | Wang, Z.,Liu, J.,Walker, N.P.C. (deposition date: 2006-11-02, release date: 2006-12-12, Last modification date: 2023-12-27) |
Primary citation | Wang, Z.,Liu, J.,Sudom, A.,Ayres, M.,Li, S.,Wesche, H.,Powers, J.P.,Walker, N.P.C. Crystal structures of IRAK-4 kinase in complex with inhibitors: a serine/threonine kinase with tyrosine as a gatekeeper. Structure, 14:1835-1844, 2006 Cited by PubMed: 17161373DOI: 10.1016/j.str.2006.11.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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