2NN6

Structure of the human RNA exosome composed of Rrp41, Rrp45, Rrp46, Rrp43, Mtr3, Rrp42, Csl4, Rrp4, and Rrp40

2NN6 の概要

• エントリーDOI: 10.2210/pdb2nn6/pdb
• 分子名称: Polymyositis/scleroderma autoantigen 1, Exosome complex exonuclease RRP41, Exosome complex exonuclease RRP43, ... (9 entities in total)
• 機能のキーワード: rna, exosome, pm/scl, exoribonuclease, phosphorolytic, ribonuclease, hydrolase-transferase complex, hydrolase/transferase
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm: Q9NPD3 Q96B26 Q9NQT5 Q13868; Nucleus, nucleolus: Q9NQT4 Q15024 Q9Y3B2; Cytoplasm (Probable): Q5RKV6
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 272665.69

構造登録者

Lima, C.D. (登録日: 2006-10-23, 公開日: 2006-12-26, 最終更新日: 2023-12-27)

• 主引用文献: Liu, Q.,Greimann, J.C.,Lima, C.D.; Reconstitution, activities, and structure of the eukaryotic RNA exosome.; Cell(Cambridge,Mass.), 127:1223-1237, 2006; PubMed: 17174896; DOI: 10.1016/j.cell.2006.10.037

実験手法

X-RAY DIFFRACTION (3.35 Å)