2N99

Solution structure of the SLURP-2, a secreted isoform of Lynx1

2N99 の概要

• エントリーDOI: 10.2210/pdb2n99/pdb
• NMR情報: BMRB: 25887
• 分子名称: Ly-6/neurotoxin-like protein 1 (1 entity in total)
• 機能のキーワード: neuromodulator, cell proliferation, three-finger protein, nicotinic acetylcholine receptor, muscarinic acetylcholine receptor, epithelium, keratinocyte, neuropeptide
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Isoform 1: Secreted . Isoform 2: Cell membrane ; Lipid-anchor, GPI-anchor . Isoform 3: Secreted: Q9BZG9
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 8163.42

構造登録者

Paramonov, A.S.,Shenkarev, Z.O.,Lyukmanova, E.N.,Arseniev, A.S. (登録日: 2015-11-11, 公開日: 2016-09-21, 最終更新日: 2023-06-14)

• 主引用文献: Lyukmanova, E.N.,Shulepko, M.A.,Shenkarev, Z.O.,Bychkov, M.L.,Paramonov, A.S.,Chugunov, A.O.,Kulbatskii, D.S.,Arvaniti, M.,Dolejsi, E.,Schaer, T.,Arseniev, A.S.,Efremov, R.G.,Thomsen, M.S.,Dolezal, V.,Bertrand, D.,Dolgikh, D.A.,Kirpichnikov, M.P.; Secreted Isoform of Human Lynx1 (SLURP-2): Spatial Structure and Pharmacology of Interactions with Different Types of Acetylcholine Receptors.; Sci Rep, 6:30698-30698, 2016; PubMed: 27485575; DOI: 10.1038/srep30698

実験手法

SOLUTION NMR