2JH0
Human Thrombin Hirugen Inhibitor complex
Summary for 2JH0
Entry DOI | 10.2210/pdb2jh0/pdb |
Related | 2JH5 2JH6 |
Descriptor | THROMBIN LIGHT CHAIN, THROMBIN HEAVY CHAIN, HIRUDIN IIIA, ... (7 entities in total) |
Functional Keywords | glycoprotein, serine protease, kringle, zymogen, thrombin, protease, disease mutation, blood coagulation, gamma-carboxyglutamic acid, protease inhibitor, serine protease inhibitor, sulfation, acute phase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Secreted, extracellular space: P00734 P28507 Secreted: P00734 |
Total number of polymer chains | 3 |
Total formula weight | 35765.20 |
Authors | Senger, S.,Chan, C.,Convery, M.A.,Hubbard, J.A.,Young, R.J.,Shah, G.P.,Watson, N.S. (deposition date: 2007-02-19, release date: 2007-05-08, Last modification date: 2013-08-07) |
Primary citation | Senger, S.,Chan, C.,Convery, M.A.,Hubbard, J.A.,Shah, G.P.,Watson, N.S.,Young, R.J. Sulfonamide-Related Conformational Effects and Their Importance in Structure-Based Design. Bioorg.Med.Chem.Lett., 17:2931-, 2007 Cited by PubMed: 17336062DOI: 10.1016/J.BMCL.2007.02.034 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
Download full validation report