2HEL
Crystal structure of a mutant EphA4 kinase domain (Y742A)
Summary for 2HEL
| Entry DOI | 10.2210/pdb2hel/pdb |
| Related | 2HEN |
| Descriptor | Eph receptor A4 (2 entities in total) |
| Functional Keywords | tyr kinase, activation, signaling protein, transferase |
| Biological source | Mus musculus (house mouse) |
| Cellular location | Membrane; Single-pass type I membrane protein (By similarity): Q80VZ2 |
| Total number of polymer chains | 1 |
| Total formula weight | 34576.84 |
| Authors | Wybenga-Groot, L.E.,Sicheri, F.,Pawson, T. (deposition date: 2006-06-21, release date: 2007-02-13, Last modification date: 2024-02-14) |
| Primary citation | Wiesner, S.,Wybenga-Groot, L.E.,Warner, N.,Lin, H.,Pawson, T.,Forman-Kay, J.D.,Sicheri, F. A change in conformational dynamics underlies the activation of Eph receptor tyrosine kinases. EMBO J., 25:4686-4696, 2006 Cited by PubMed: 16977320DOI: 10.1038/sj.emboj.7601315 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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