2HEN
Crystal Structure of the EphB2 Receptor Kinase domain in complex with ADP
Summary for 2HEN
Entry DOI | 10.2210/pdb2hen/pdb |
Related | 1JPA 2HEL |
Descriptor | Ephrin type-B receptor 2, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | eph kinase domain, activation, transferase |
Biological source | Mus musculus (house mouse) |
Cellular location | Membrane; Single-pass type I membrane protein: P54763 |
Total number of polymer chains | 4 |
Total formula weight | 130946.30 |
Authors | Wybenga-Groot, L.E.,Sicheri, F.,Pawson, T. (deposition date: 2006-06-21, release date: 2007-02-13, Last modification date: 2024-02-14) |
Primary citation | Wiesner, S.,Wybenga-Groot, L.E.,Warner, N.,Lin, H.,Pawson, T.,Forman-Kay, J.D.,Sicheri, F. A change in conformational dynamics underlies the activation of Eph receptor tyrosine kinases EMBO J., 25:4686-4696, 2006 Cited by PubMed: 16977320DOI: 10.1038/sj.emboj.7601315 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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