2H9V

Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y27632

Summary for 2H9V

• Entry DOI: 10.2210/pdb2h9v/pdb
• Related: 2F2U
• Descriptor: Rho-associated protein kinase 2, (R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE (3 entities in total)
• Functional Keywords: protein kinase-inhibitor complex, transferase
• Biological source: Bos taurus (cattle)
• Cellular location: Cytoplasm: Q28021
• Total number of polymer chains: 1
• Total formula weight: 46023.36

Authors

Yamaguchi, H.,Miwa, Y.,Kasa, M.,Kitano, K.,Amano, M.,Kaibuchi, K.,Hakoshima, T. (deposition date: 2006-06-12, release date: 2006-12-05, Last modification date: 2024-03-13)

• Primary citation: Yamaguchi, H.,Miwa, Y.,Kasa, M.,Kitano, K.,Amano, M.,Kaibuchi, K.,Hakoshima, T.; Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y-27632; J.Biochem.(Tokyo), 140:305-311, 2006; PubMed: 16891330; DOI: 10.1093/jb/mvj172

Experimental method

X-RAY DIFFRACTION (3.1 Å)