2GWF

Structure of a USP8-NRDP1 complex

Summary for 2GWF

Entry DOI	10.2210/pdb2gwf/pdb
Related	1WHB 2A9U 2FZP 2GFO
Descriptor	Ubiquitin carboxyl-terminal hydrolase 8, RING finger protein 41 (3 entities in total)
Functional Keywords	protein-protein complex, e3 ligase, protein ubiquitination, hydrolase, protease, ubl conjugation pathway, structural genomics, structural genomics consortium, sgc, hydrolase-ligase complex, hydrolase/ligase
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm: P40818
Total number of polymer chains	6
Total formula weight	98292.61
Authors	Walker, J.R.,Avvakumov, G.V.,Xue, S.,Newman, E.M.,Butler-Cole, C.,Finerty Jr., P.J.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (deposition date: 2006-05-04, release date: 2006-06-06, Last modification date: 2024-02-14)
Primary citation	Avvakumov, G.V.,Walker, J.R.,Xue, S.,Finerty Jr., P.J.,Mackenzie, F.,Newman, E.M.,Dhe-Paganon, S. Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8). J.Biol.Chem., 281:38061-38070, 2006 Cited by PubMed: 17035239 DOI: 10.1074/jbc.M606704200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation