2FD0

HIV-1 DIS kissing-loop in complex with lividomycin

Summary for 2FD0

• Entry DOI: 10.2210/pdb2fd0/pdb
• Related: 2FCX 2FCY 2FCZ
• Descriptor: HIV-1 DIS RNA, (2R,3S,4S,5S,6R)-2-((2S,3S,4R,5R,6R)-5-AMINO-2-(AMINOMETHYL)-6-((2R,3S,4R,5S)-5-((1R,2R,3S,5R,6S)-3,5-DIAMINO-2-((2S,3R ,5S,6R)-3-AMINO-5-HYDROXY-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-6-HYDROXYCYCLOHEXYLOXY)-4-HYDROXY-2-(HYDROXYMET HYL)-TETRAHYDROFURAN-3-YLOXY)-4-HYDROXY-TETRAHYDRO-2H-PYRAN-3-YLOXY)-6-(HYDROXYMETHYL)-TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL, POTASSIUM ION, ... (5 entities in total)
• Functional Keywords: hiv-1, rna, aminoglycoside, antibiotics
• Total number of polymer chains: 2
• Total formula weight: 16646.12

Authors

Ennifar, E.,Paillart, J.C.,Marquet, R.,Dumas, P. (deposition date: 2005-12-13, release date: 2006-05-16, Last modification date: 2023-08-30)

• Primary citation: Ennifar, E.,Paillart, J.C.,Bodlenner, A.,Walter, P.,Weibel, J.-M.,Aubertin, A.-M.,Pale, P.,Dumas, P.,Marquet, R.; Targeting the dimerization initiation site of HIV-1 RNA with aminoglycosides: from crystal to cell.; Nucleic Acids Res., 34:2328-2339, 2006; PubMed: 16679451; DOI: 10.1093/nar/gkl317

Experimental method

X-RAY DIFFRACTION (1.8 Å)