2F1Y
Crystal structure of the TRAF-like domain of HAUSP/USP7 bound to a MDM2 peptide
Summary for 2F1Y
Entry DOI | 10.2210/pdb2f1y/pdb |
Related | 2F1W 2F1X |
Descriptor | HAUSP/USP7 (2 entities in total) |
Functional Keywords | hausp, usp7, mdm2, ubp, traf_like domain, mdm2 recognition, substrate binding, hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus, nucleoplasm: Q00987 |
Total number of polymer chains | 1 |
Total formula weight | 18555.51 |
Authors | Hu, M.,Gu, L.,Jeffrey, P.D.,Shi, Y. (deposition date: 2005-11-15, release date: 2006-02-07, Last modification date: 2023-08-23) |
Primary citation | Hu, M.,Gu, L.,Li, M.,Jeffrey, P.D.,Gu, W.,Shi, Y. Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway. Plos Biol., 4:e27-e27, 2006 Cited by PubMed: 16402859DOI: 10.1371/journal.pbio.0040027 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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