2DKO
Extended substrate recognition in caspase-3 revealed by high resolution X-ray structure analysis
Summary for 2DKO
Entry DOI | 10.2210/pdb2dko/pdb |
Related PRD ID | PRD_000277 |
Descriptor | Caspase-3, PHQ-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE, ... (4 entities in total) |
Functional Keywords | low barrier hydrogen bond, caspase, drug design, radiation damage, tetrahedral intermediate, protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P42574 P42574 |
Total number of polymer chains | 3 |
Total formula weight | 29167.98 |
Authors | Mittl, P.R.E.,Ganesan, R.,Jelakovic, S.,Grutter, M.G. (deposition date: 2006-04-12, release date: 2006-07-04, Last modification date: 2023-10-25) |
Primary citation | Ganesan, R.,Mittl, P.R.E.,Jelakovic, S.,Grutter, M.G. Extended Substrate Recognition in Caspase-3 Revealed by High Resolution X-ray Structure Analysis J.Mol.Biol., 359:1378-1388, 2006 Cited by PubMed: 16787777DOI: 10.1016/j.jmb.2006.04.051 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.06 Å) |
Structure validation
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