2DKO
Extended substrate recognition in caspase-3 revealed by high resolution X-ray structure analysis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Caspase-3 | polymer | 146 | 16524.8 | 1 | UniProt (P42574) Pfam (PF00656) In PDB | Homo sapiens (human) | |
| 2 | B | Caspase-3 | polymer | 103 | 11981.7 | 1 | UniProt (P42574) Pfam (PF00656) In PDB | Homo sapiens (human) | |
| 3 | I | PHQ-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE | polymer | 6 | 661.5 | 1 | BIRD (PRD_000277) | Z-DEVD-CMK | |
| 4 | water | water | 18.0 | 335 | Chemie (HOH) |
Sequence modifications
B: 175 - 277 (UniProt: P42574)
| PDB | External Database | Details |
|---|---|---|
| Ala 175 | Asp 175 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 29168.0 | |
| All* | Total formula weight | 29168.0 |
