2C57

H.pylori type II dehydroquinase in complex with FA1

Summary for 2C57

Entry DOI	10.2210/pdb2c57/pdb
Related	1J2Y 2C4V 2C4W
Descriptor	3-DEHYDROQUINATE DEHYDRATASE, 2,3 -ANHYDRO-QUINIC ACID (2 entities in total)
Functional Keywords	dehydroquinase, dehydroquinate, sulphonamide, lyase, 3-dehydroquinase, shikimate pathway, aromatic amino acid biosynthesis
Biological source	HELICOBACTER PYLORI
Total number of polymer chains	12
Total formula weight	241594.39
Authors	Robinson, D.A.,Lapthorn, A.J. (deposition date: 2005-10-26, release date: 2006-02-22, Last modification date: 2023-12-13)
Primary citation	Robinson, D.A.,Stewart, K.A.,Price, N.C.,Chalk, P.A.,Coggins, J.R.,Lapthorn, A.J. Crystal Structures of Helicobacter Pylori Type II Dehydroquinase Inhibitor Complexes: New Directions for Inhibitor Design. J.Med.Chem., 49:1282-, 2006 Cited by PubMed: 16480265 DOI: 10.1021/JM0505361 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation