2C4W
Type II Dehydroquinase from H. pylori in complex with AH9095
Summary for 2C4W
| Entry DOI | 10.2210/pdb2c4w/pdb |
| Related | 1J2Y 2C4V 2C57 |
| Descriptor | 3-DEHYDROQUINATE DEHYDRATASE, N-TETRAZOL-5-YL 9-OXO-9H-XANTHENE-2 SULPHONAMIDE, GLYCEROL, ... (5 entities in total) |
| Functional Keywords | 3-dehydroquinase, shikimate pathway, aromatic amino acid biosynthesis, lyase, dehydroquinate, sulphonamide |
| Biological source | HELICOBACTER PYLORI |
| Total number of polymer chains | 1 |
| Total formula weight | 20055.95 |
| Authors | Robinson, D.A.,Lapthorn, A.J. (deposition date: 2005-10-24, release date: 2006-02-22, Last modification date: 2023-12-13) |
| Primary citation | Robinson, D.A.,Stewart, K.A.,Price, N.C.,Chalk, P.A.,Coggins, J.R.,Lapthorn, A.J. Crystal Structures of Helicobacter Pylori Type II Dehydroquinase Inhibitor Complexes: New Directions for Inhibitor Design. J.Med.Chem., 49:1282-, 2006 Cited by PubMed: 16480265DOI: 10.1021/JM0505361 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
Download full validation report
