2AHB
X-ray crystal structure of R46A,R161A mutant of Mycobacterium tuberculosis FabH
Summary for 2AHB
Entry DOI | 10.2210/pdb2ahb/pdb |
Related | 1HZP 1M1M |
Descriptor | Beta- ketoacyl-ACP synthase III (2 entities in total) |
Functional Keywords | 3-oxoacyl-[acyl-carrier-protein] synthase iii, beta-ketoacyl-acyl carrier protein synthase iii, mtfabh, fabh, transferase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 2 |
Total formula weight | 73933.28 |
Authors | Brown, A.K.,Sridharan, S.,Kremer, L.,Lindenberg, S.,Dover, L.G.,Sacchettini, J.C.,Besra, G.S. (deposition date: 2005-07-27, release date: 2005-08-23, Last modification date: 2023-08-23) |
Primary citation | Brown, A.K.,Sridharan, S.,Kremer, L.,Lindenberg, S.,Dover, L.G.,Sacchettini, J.C.,Besra, G.S. Probing the Mechanism of the Mycobacterium tuberculosis {beta}-Ketoacyl-Acyl Carrier Protein Synthase III mtFabH: FACTORS INFLUENCING CATALYSIS AND SUBSTRATE SPECIFICITY J.Biol.Chem., 280:32539-32547, 2005 Cited by PubMed: 16040614DOI: 10.1074/jbc.M413216200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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