1M1M

X-RAY CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III (MTFABH)

Summary for 1M1M

• Entry DOI: 10.2210/pdb1m1m/pdb
• Descriptor: 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE III (2 entities in total)
• Functional Keywords: 3-oxoacyl-acyl carrier protein synthase iii, mtfabh, condensing enzyme, alpha-beta-alpha-beta-alpha, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc, transferase
• Biological source: Mycobacterium tuberculosis
• Cellular location: Cytoplasm: P0A574
• Total number of polymer chains: 2
• Total formula weight: 74149.49

Authors

Sacchettini, J.C.,Sridharan, S.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2002-06-19, release date: 2002-07-17, Last modification date: 2024-02-14)

• Primary citation: Brown, A.K.,Sridharan, S.,Kremer, L.,Lindenberg, S.,Dover, L.G.,Sacchettini, J.C.,Besra, G.S.; Probing the mechanism of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III mtFabH: factors influencing catalysis and substrate specificity.; J.Biol.Chem., 280:32539-32547, 2005; PubMed: 16040614; DOI: 10.1074/jbc.M413216200

Experimental method

X-RAY DIFFRACTION (2.7 Å)