2ADO

Crystal Structure Of The Brct Repeat Region From The Mediator of DNA damage checkpoint protein 1, MDC1

Summary for 2ADO

Entry DOI	10.2210/pdb2ado/pdb
Descriptor	Mediator of DNA damage checkpoint protein 1 (2 entities in total)
Functional Keywords	brct repeats, cell cycle
Biological source	Homo sapiens (human)
Cellular location	Nucleus : Q14676
Total number of polymer chains	2
Total formula weight	43019.91
Authors	Lee, M.S.,Edwards, R.A.,Thede, G.L.,Glover, J.N. (deposition date: 2005-07-20, release date: 2005-08-02, Last modification date: 2024-02-14)
Primary citation	Lee, M.S.,Edwards, R.A.,Thede, G.L.,Glover, J.N. Structure of the BRCT Repeat Domain of MDC1 and Its Specificity for the Free COOH-terminal End of the {gamma}-H2AX Histone Tail. J.Biol.Chem., 280:32053-32056, 2005 Cited by PubMed: 16049003 DOI: 10.1074/jbc.C500273200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation