1V3Q
Structure of human PNP complexed with DDI
Summary for 1V3Q
Entry DOI | 10.2210/pdb1v3q/pdb |
Related | 1M73 1PF7 1RCT 1V41 1V45 |
Descriptor | Purine nucleoside phosphorylase, SULFATE ION, 9-[(2R,5R)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL]-1,9-DIHYDRO-6H-PURIN-6-ONE, ... (4 entities in total) |
Functional Keywords | purine nucleoside phosphorylase, drug design, synchrotorn, ddi, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytoskeleton (By similarity): P00491 |
Total number of polymer chains | 1 |
Total formula weight | 32578.10 |
Authors | Canduri, F.,Pereira, J.H.,dos Santos, D.M.,Silva, R.G.,Palma, M.S.,Basso, L.A.,de Azevedo Jr., W.F.,Santos, D.S. (deposition date: 2003-11-04, release date: 2004-01-20, Last modification date: 2023-10-25) |
Primary citation | Canduri, F.,dos Santos, D.M.,Silva, R.G.,Mendes, M.A.,Basso, L.A.,Palma, M.S.,de Azevedo Jr., W.F.,Santos, D.S. Structures of human purine nucleoside phosphorylase complexed with inosine and ddI Biochem.Biophys.Res.Commun., 313:907-914, 2004 Cited by PubMed: 14706628DOI: 10.1016/j.bbrc.2003.11.179 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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