1V41

Crystal structure of human PNP complexed with 8-Azaguanine

Summary for 1V41

• Entry DOI: 10.2210/pdb1v41/pdb
• Related: 1V3Q 1V45
• Descriptor: Purine nucleoside phosphorylase, SULFATE ION, 5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL, ... (4 entities in total)
• Functional Keywords: purine nucleoside phosphorylase, drug design, sybcgritron, 8-azaguanine, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, cytoskeleton (By similarity): P00491
• Total number of polymer chains: 1
• Total formula weight: 32590.05

Authors

Dos Santos, D.M.,Canduri, F.,Silva, R.G.,Mendes, M.A.,Basso, L.A.,Palma, M.S.,De Azevedo Jr., W.F.,Santos, D.S. (deposition date: 2003-11-08, release date: 2004-12-14, Last modification date: 2023-10-25)

• Primary citation: Canduri, F.,Silva, R.G.,dos Santos, D.M.,Palma, M.S.,Basso, L.A.,Santos, D.S.,de Azevedo Jr., W.F.; Structure of human PNP complexed with ligands.; Acta Crystallogr.,Sect.D, 61:856-862, 2005; PubMed: 15983407; DOI: 10.1107/S0907444905005421

Experimental method

X-RAY DIFFRACTION (2.85 Å)