1TC0
Ligand Induced Conformational Shifts in the N-terminal Domain of GRP94, Open Conformation Complexed with the physiological partner ATP
Summary for 1TC0
Entry DOI | 10.2210/pdb1tc0/pdb |
Related | 1QY5 1QY8 1QYE 1QYH 1TBW 1TC6 |
Descriptor | Endoplasmin, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | grp94, hsp90, atp, bergerat, chaperone, endoplasmic reticulum |
Biological source | Canis lupus familiaris (dog) More |
Cellular location | Endoplasmic reticulum lumen: P41148 |
Total number of polymer chains | 2 |
Total formula weight | 55062.13 |
Authors | Gewirth, D.T.,Immormino, R.M.,Dollins, D.E.,Shaffer, P.L.,Walker, M.A.,Soldano, K.L. (deposition date: 2004-05-20, release date: 2004-08-24, Last modification date: 2024-02-14) |
Primary citation | Immormino, R.M.,Dollins, D.E.,Shaffer, P.L.,Soldano, K.L.,Walker, M.A.,Gewirth, D.T. Ligand-induced Conformational Shift in the N-terminal Domain of GRP94, an Hsp90 Chaperone. J.Biol.Chem., 279:46162-46171, 2004 Cited by PubMed: 15292259DOI: 10.1074/jbc.M405253200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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