1SI3

Crystal structure of the PAZ domain of human eIF2c1 in complex with a 9-mer siRNA-like duplex

Summary for 1SI3

• Entry DOI: 10.2210/pdb1si3/pdb
• Related: 1SI2
• Descriptor: 5'-R(*CP*GP*UP*GP*AP*CP*UP*CP*U)-3', Eukaryotic translation initiation factor 2C 1 (3 entities in total)
• Functional Keywords: protein-rna complex, rna interference, double helix, overhang, gene regulation-rna complex, gene regulation/rna
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, P-body: Q9UL18
• Total number of polymer chains: 2
• Total formula weight: 20186.27

Authors

Ye, K.,Ma, J.B.,Patel, D. (deposition date: 2004-02-27, release date: 2004-05-25, Last modification date: 2011-07-13)

• Primary citation: Ma, J.B.,Ye, K.,Patel, D.J.; Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain.; Nature, 429:318-322, 2004; PubMed: 15152257; DOI: 10.1038/nature02519

Experimental method

X-RAY DIFFRACTION (2.6 Å)