1SC3
Crystal structure of the human caspase-1 C285A mutant in complex with malonate
Summary for 1SC3
Entry DOI | 10.2210/pdb1sc3/pdb |
Related | 1sc1 1SC4 |
Descriptor | Interleukin-1 beta convertase, MALONATE ION, ... (4 entities in total) |
Functional Keywords | malonate-bound caspase-1, hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: P29466 P29466 |
Total number of polymer chains | 2 |
Total formula weight | 30198.57 |
Authors | Romanowski, M.J.,Scheer, J.M.,O'Brien, T.,McDowell, R.S. (deposition date: 2004-02-11, release date: 2004-08-10, Last modification date: 2023-08-23) |
Primary citation | Romanowski, M.J.,Scheer, J.M.,O'Brien, T.,McDowell, R.S. Crystal structures of a ligand-free and malonate-bound human caspase-1: implications for the mechanism of substrate binding. Structure, 12:1361-1371, 2004 Cited by PubMed: 15296730DOI: 10.1016/j.str.2004.05.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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