1R00

Crystal structure of aclacinomycin-10-hydroxylase (RdmB) in complex with S-adenosyl-L-homocysteine (SAH)

Summary for 1R00

Entry DOI	10.2210/pdb1r00/pdb
Related	1QZZ
Descriptor	aclacinomycin-10-hydroxylase, ACETATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total)
Functional Keywords	anthracycline, hydroxylase, methyltransferase, polyketide, streptomyces, tailoring enzyme, oxidoreductase, transferase
Biological source	Streptomyces purpurascens
Total number of polymer chains	1
Total formula weight	40281.40
Authors	Jansson, A.,Niemi, J.,Lindqvist, Y.,Mantsala, P.,Schneider, G. (deposition date: 2003-09-19, release date: 2003-11-25, Last modification date: 2023-08-23)
Primary citation	Jansson, A.,Niemi, J.,Lindqvist, Y.,Mantsala, P.,Schneider, G. Crystal Structure of Aclacinomycin-10-Hydroxylase, a S-Adenosyl-L-Methionine-dependent Methyltransferase Homolog Involved in Anthracycline Biosynthesis in Streptomyces purpurascens. J.Mol.Biol., 334:269-280, 2003 Cited by PubMed: 14607118 DOI: 10.1016/j.jmb.2003.09.061 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation