1QZZ

Crystal structure of aclacinomycin-10-hydroxylase (RdmB) in complex with S-adenosyl-L-methionine (SAM)

Summary for 1QZZ

• Entry DOI: 10.2210/pdb1qzz/pdb
• Related: 1R00
• Descriptor: aclacinomycin-10-hydroxylase, ACETATE ION, S-ADENOSYLMETHIONINE, ... (4 entities in total)
• Functional Keywords: anthracycline, hydroxylase, methyltransferase, polyketide, streptomyces, tailoring enzymes, structural proteomics in europe, spine, structural genomics, oxidoreductase, transferase
• Biological source: Streptomyces purpurascens
• Total number of polymer chains: 1
• Total formula weight: 40295.43

Authors

Jansson, A.,Niemi, J.,Lindqvist, Y.,Mantsala, P.,Schneider, G.,Structural Proteomics in Europe (SPINE) (deposition date: 2003-09-19, release date: 2003-11-25, Last modification date: 2024-02-14)

• Primary citation: Jansson, A.,Niemi, J.,Lindqvist, Y.,Mantsala, P.,Schneider, G.; Crystal Structure of Aclacinomycin-10-Hydroxylase, a S-Adenosyl-L-Methionine-dependent Methyltransferase Homolog Involved in Anthracycline Biosynthesis in Streptomyces purpurascens.; J.Mol.Biol., 334:269-280, 2003; PubMed: 14607118; DOI: 10.1016/j.jmb.2003.09.061

Experimental method

X-RAY DIFFRACTION (2.1 Å)