1QBY

THE SOLUTION STRUCTURE OF A BAY-REGION 1R-BENZ[A]ANTHRACENE OXIDE ADDUCT AT THE N6 POSITION OF ADENINE OF AN OLIGODEOXYNUCLEOTIDE CONTAINING THE HUMAN N-RAS CODON 61 SEQUENCE

1QBY の概要

• エントリーDOI: 10.2210/pdb1qby/pdb
• 分子名称: 5'-D(*CP*GP*GP*AP*CP*(BZA)AP*AP*GP*AP*AP*G)-3', 5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP* G)-3', 1R,2S,3R,4S-TETRAHYDRO-BENZO[A]ANTHRACENE-2,3,4-TRIOL (3 entities in total)
• 機能のキーワード: benz[a]anthracene-dna duplex, intercalation, dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 6987.73

構造登録者

Li, Z.,Mao, H.,Kim, H.-Y.,Tamura, P.J.,Harris, C.M.,Harris, T.M.,Stone, M.P. (登録日: 1999-04-27, 公開日: 1999-05-06, 最終更新日: 2022-03-02)

• 主引用文献: Li, Z.,Mao, H.,Kim, H.Y.,Tamura, P.J.,Harris, C.M.,Harris, T.M.,Stone, M.P.; Intercalation of the (-)-(1R,2S,3R, 4S)-N6-[1-benz[a]anthracenyl]-2'-deoxyadenosyl adduct in an oligodeoxynucleotide containing the human N-ras codon 61 sequence.; Biochemistry, 38:2969-2981, 1999; PubMed: 10074349; DOI: 10.1021/bi982072x

実験手法

SOLUTION NMR