1P9A

Crystal Structure of N-Terminal Domain of Human Platelet Receptor Glycoprotein Ib-alpha at 1.7 Angstrom Resolution

Summary for 1P9A

• Entry DOI: 10.2210/pdb1p9a/pdb
• Related: 1OOK
• Descriptor: Platelet glycoprotein Ib alpha chain precursor, beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: platelet receptors, glycocalicin, leucine rich repeats, blood clotting
• Biological source: Homo sapiens (human)
• Cellular location: Membrane; Single-pass type I membrane protein: P07359
• Total number of polymer chains: 1
• Total formula weight: 33055.47

Authors

Varughese, K.I.,Celikel, R.,Ruggeri, Z.M. (deposition date: 2003-05-09, release date: 2003-07-22, Last modification date: 2024-04-03)

• Primary citation: Celikel, R.,McClintock, R.A.,Roberts, J.R.,Mendolicchio, G.L.,Ware, J.,Varughese, K.I.,Ruggeri, Z.M.; Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha; Science, 301:218-221, 2003; PubMed: 12855810; DOI: 10.1126/science.1084183

Experimental method

X-RAY DIFFRACTION (1.7 Å)