1OOK

Crystal Structure of the Complex of Platelet Receptor GPIb-alpha and Human alpha-Thrombin

Summary for 1OOK

Entry DOI	10.2210/pdb1ook/pdb
Descriptor	Human Alpha Thrombin, PHE-PRO-ARG-Chloromethylketone, Platelet glycoprotein Ib alpha chain precursor, ... (8 entities in total)
Functional Keywords	leucine rich repeats, hydrolase
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	67930.65
Authors	Varughese, K.I.,Celikel, R.,Ruggeri, Z.M. (deposition date: 2003-03-03, release date: 2003-07-22, Last modification date: 2021-10-27)
Primary citation	Celikel, R.,McClintock, R.A.,Roberts, J.R.,Mendolicchio, G.L.,Ware, J.,Varughese, K.I.,Ruggeri, Z.M. Modulation of alpha-thrombin function by distinct interactions with platelet glycoprotein Ibalpha Science, 301:218-221, 2003 Cited by PubMed: 12855810 DOI: 10.1126/science.1084183 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation