1NQ9
Crystal Structure of Antithrombin in the Pentasaccharide-Bound Intermediate State
Summary for 1NQ9
Entry DOI | 10.2210/pdb1nq9/pdb |
Related | 1E03 1E04 1E05 1OYH |
Related PRD ID | PRD_900031 |
Descriptor | Antithrombin-III, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3,4-di-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-beta-D-glucopyranuronic acid-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-3-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2,3,6-tri-O-sulfo-alpha-D-glucopyranoside, ... (5 entities in total) |
Functional Keywords | thrombin; inhibition; heparin analogue; serine protease inhibitor, blood clotting |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P01008 |
Total number of polymer chains | 2 |
Total formula weight | 103240.48 |
Authors | Huntington, J.A.,Johnson, D.J.D. (deposition date: 2003-01-21, release date: 2003-09-30, Last modification date: 2024-03-13) |
Primary citation | Johnson, D.J.D.,Huntington, J.A. Crystal Structure of Antithrombin in a Heparin-Bound Intermediate State Biochemistry, 42:8712-8719, 2003 Cited by PubMed: 12873131DOI: 10.1021/bi034524y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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