1NDZ
Crystal Structure of Adenosine Deaminase Complexed with FR235999
Summary for 1NDZ
Entry DOI | 10.2210/pdb1ndz/pdb |
Related | 1NDV 1NDW 1NDY |
Descriptor | Adenosine Deaminase, ZINC ION, 1-((1R)-1-(HYDROXYMETHYL)-3-(6-((3-(1-METHYL-1H-BENZIMIDAZOL-2-YL)PROPANOYL)AMINO)-1H-INDOL-1-YL)PROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE, ... (4 entities in total) |
Functional Keywords | sbdd, tim-barrel, hydrolase |
Biological source | Bos taurus (cattle) |
Cellular location | Cell membrane; Peripheral membrane protein; Extracellular side (By similarity): P56658 |
Total number of polymer chains | 1 |
Total formula weight | 40906.64 |
Authors | Kinoshita, T. (deposition date: 2002-12-09, release date: 2003-12-09, Last modification date: 2024-03-13) |
Primary citation | Terasaka, T.,Kinoshita, T.,Kuno, M.,Nakanishi, I. A highly potent non-nucleoside adenosine deaminase inhibitor: efficient drug discovery by intentional lead hybridization J.Am.Chem.Soc., 126:34-35, 2004 Cited by PubMed: 14709046DOI: 10.1021/ja038606l PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report