1MV9

Crystal Structure of the human RXR alpha ligand binding domain bound to the eicosanoid DHA (Docosa Hexaenoic Acid) and a coactivator peptide

Summary for 1MV9

• Entry DOI: 10.2210/pdb1mv9/pdb
• Related: 1FBY 1MVC
• Descriptor: RXR retinoid X receptor, Nuclear receptor coactivator 2, DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, ... (4 entities in total)
• Functional Keywords: transcription regulation, nuclear protein, transcription
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P19793 Q15596
• Total number of polymer chains: 2
• Total formula weight: 28764.39

Authors

Egea, P.F.,Mitschler, A.,Moras, D. (deposition date: 2002-09-24, release date: 2002-10-16, Last modification date: 2023-10-25)

• Primary citation: Egea, P.F.,Mitschler, A.,Moras, D.; Molecular Recognition of Agonist Ligands by RXRs; MOL.ENDOCRINOL., 16:987-997, 2002; PubMed: 11981034; DOI: 10.1210/me.16.5.987

Experimental method

X-RAY DIFFRACTION (1.9 Å)