1LO6

Human Kallikrein 6 (hK6) active form with benzamidine inhibitor at 1.56 A resolution

Summary for 1LO6

• Entry DOI: 10.2210/pdb1lo6/pdb
• Related: 1L2E
• Descriptor: Kallikrein 6, MAGNESIUM ION, BENZAMIDINE, ... (4 entities in total)
• Functional Keywords: serine protease, kallikrein, human kallikrein 6, hk6, benzamidine, protease, brain serine protease, myelencephalon specific protease, msp, zyme, protease m, neurosin, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: Q92876
• Total number of polymer chains: 1
• Total formula weight: 24677.33

Authors

Bernett, M.J.,Blaber, S.I.,Scarisbrick, I.A.,Dhanarajan, P.,Thompson, S.M.,Blaber, M. (deposition date: 2002-05-06, release date: 2002-05-15, Last modification date: 2023-08-16)

• Primary citation: Bernett, M.J.,Blaber, S.I.,Scarisbrick, I.A.,Dhanarajan, P.,Thompson, S.M.,Blaber, M.; Crystal structure and biochemical characterization of human kallikrein 6 reveals a trypsin-like kallikrein is expressed in the central nervous system; To be Published,

Experimental method

X-RAY DIFFRACTION (1.56 Å)