1L2E

Human Kallikrein 6 (hK6) Active Form with benzamidine inhibitor

Summary for 1L2E

Entry DOI	10.2210/pdb1l2e/pdb
Descriptor	Kallikrein 6, MAGNESIUM ION, BENZAMIDINE, ... (4 entities in total)
Functional Keywords	serine protease, kallikrein, human kallikrein 6, benzamidine, protease, myelencephalon specific protease, zyme, protease m, neurosin, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Secreted: Q92876
Total number of polymer chains	1
Total formula weight	24677.33
Authors	Bernett, M.J.,Blaber, S.I.,Scarisbrick, I.A.,Blaber, M. (deposition date: 2002-02-20, release date: 2002-05-08, Last modification date: 2023-08-16)
Primary citation	Bernett, M.J.,Blaber, S.I.,Scarisbrick, I.A.,Dhanarajan, P.,Thompson, S.M.,Blaber, M. Crystal structure and biochemical characterization of human kallikrein 6 reveals that a trypsin-like kallikrein is expressed in the central nervous system. J.Biol.Chem., 277:24562-24570, 2002 Cited by PubMed: 11983703 DOI: 10.1074/jbc.M202392200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation