1LK3
ENGINEERED HUMAN INTERLEUKIN-10 MONOMER COMPLEXED TO 9D7 FAB FRAGMENT
Summary for 1LK3
Entry DOI | 10.2210/pdb1lk3/pdb |
Related | 1J7V |
Descriptor | Interleukin-10, 9D7 Light Chain, 9D7 Heavy Chain, ... (4 entities in total) |
Functional Keywords | antigen-antibody complex, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P22301 |
Total number of polymer chains | 6 |
Total formula weight | 129688.41 |
Authors | Josephson, K.,Jones, B.C.,Walter, L.J.,DiGiacomo, R.,Indelicato, S.R.,Walter, M.R. (deposition date: 2002-04-23, release date: 2002-07-17, Last modification date: 2011-07-13) |
Primary citation | Josephson, K.,Jones, B.C.,Walter, L.J.,DiGiacomo, R.,Indelicato, S.R.,Walter, M.R. Noncompetitive antibody neutralization of IL-10 revealed by protein engineering and x-ray crystallography. Structure, 10:981-987, 2002 Cited by PubMed: 12121653DOI: 10.1016/S0969-2126(02)00791-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.91 Å) |
Structure validation
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