1J7V

HUMAN IL-10 / IL-10R1 COMPLEX

Summary for 1J7V

• Entry DOI: 10.2210/pdb1j7v/pdb
• Descriptor: INTERLEUKIN-10, INTERLEUKIN-10 RECEPTOR ALPHA CHAIN (3 entities in total)
• Functional Keywords: cytokine receptor complex, 4 helix bundle, class 2 receptor, interleukin-10, cytokine-receptor complex, cytokine/receptor
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P22301; Membrane; Single-pass type I membrane protein: Q13651
• Total number of polymer chains: 2
• Total formula weight: 43179.00

Authors

Josephson, K.,Logsdon, N.,Walter, M.R. (deposition date: 2001-05-18, release date: 2001-09-19, Last modification date: 2021-10-27)

• Primary citation: Josephson, K.,Logsdon, N.J.,Walter, M.R.; Crystal structure of the IL-10/IL-10R1 complex reveals a shared receptor binding site.; Immunity, 15:35-46, 2001; PubMed: 11485736; DOI: 10.1016/S1074-7613(01)00169-8

Experimental method

X-RAY DIFFRACTION (2.9 Å)