1LE5
Crystal structure of a NF-kB heterodimer bound to an IFNb-kB
Summary for 1LE5
Entry DOI | 10.2210/pdb1le5/pdb |
Related | 1LE9 1LEI 1VKX |
Descriptor | 5'-D(*TP*GP*GP*GP*AP*AP*AP*TP*TP*CP*CP*T)-3', 5'-D(*AP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*C)-3', Nuclear factor NF-kappa-B p65 subunit, ... (5 entities in total) |
Functional Keywords | protein-dna complex, transcription factors, rel/nf-kb protein, transcription-dna complex, transcription/dna |
Biological source | Mus musculus (house mouse) More |
Cellular location | Nucleus: Q04207 Nucleus. Isoform 5: Cytoplasm. Isoform 6: Nucleus. Isoform 7: Nucleus: P25799 |
Total number of polymer chains | 8 |
Total formula weight | 146990.24 |
Authors | Berkowitz, B.,Huang, D.B.,Chen-Park, F.E.,Sigler, P.B.,Ghosh, G. (deposition date: 2002-04-09, release date: 2003-04-15, Last modification date: 2023-09-20) |
Primary citation | Berkowitz, B.,Huang, D.B.,Chen-Park, F.E.,Sigler, P.B.,Ghosh, G. The X-ray crystal structure of the NF-kB p50/p65 heterodimer bound to the Interferon beta-kB site J.Biol.Chem., 277:24694-24700, 2002 Cited by PubMed: 11970948DOI: 10.1074/jbc.M200006200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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