1LEI

The kB DNA sequence from the HLV-LTR functions as an allosteric regulator of HIV transcription

Summary for 1LEI

• Entry DOI: 10.2210/pdb1lei/pdb
• Related: 1VKX
• Descriptor: 5'-D(*CP*TP*CP*AP*GP*GP*GP*AP*AP*AP*GP*TP*AP*CP*AP*GP*A)-3', 5'-D(*TP*CP*TP*GP*5ITP*AP*CP*5ITP*5ITP*5ITP*CP*CP*CP*TP*GP*AP*G)-3', NUCLEAR FACTOR NF-KAPPA-B P65 SUBUNIT, ... (5 entities in total)
• Functional Keywords: transcription factor, nf-kb-dna complex, transcription-dna complex, transcription/dna
• Biological source: Mus musculus (house mouse); More
• Cellular location: Nucleus: 1LEI; Nucleus. Isoform 5: Cytoplasm. Isoform 6: Nucleus. Isoform 7: Nucleus: 1LEI
• Total number of polymer chains: 4
• Total formula weight: 77032.56

Authors

Chen-Park, F.,Huang, D.B.,Ghosh, G. (deposition date: 2002-04-09, release date: 2003-04-15, Last modification date: 2023-09-20)

• Primary citation: Chen-Park, F.E.,Huang, D.B.,Noro, B.,Thanos, D.,Ghosh, G.; The kB DNA sequence from the HIV Long Terminal Repeat functions as an allosteric regulator of HIV transcription; J.Biol.Chem., 277:24701-24708, 2002; PubMed: 11970949; DOI: 10.1074/jbc.M200007200

Experimental method

X-RAY DIFFRACTION (2.7 Å)