1KDX

KIX DOMAIN OF MOUSE CBP (CREB BINDING PROTEIN) IN COMPLEX WITH PHOSPHORYLATED KINASE INDUCIBLE DOMAIN (PKID) OF RAT CREB (CYCLIC AMP RESPONSE ELEMENT BINDING PROTEIN), NMR 17 STRUCTURES

1KDX の概要

• エントリーDOI: 10.2210/pdb1kdx/pdb
• 分子名称: CBP, CREB (2 entities in total)
• 機能のキーワード: complex (transcription activator-co-activator), protein-protein interaction, phosphoserine recognition, transcription regulation complex
• 由来する生物種: Mus musculus (house mouse); 詳細
• 細胞内の位置: Cytoplasm (By similarity): P45481; Nucleus: P15337
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 12942.56

構造登録者

Radhakrishnan, I.,Perez-Alvarado, G.C.,Dyson, H.J.,Wright, P.E. (登録日: 1997-09-16, 公開日: 1998-11-25, 最終更新日: 2021-11-03)

• 主引用文献: Radhakrishnan, I.,Perez-Alvarado, G.C.,Parker, D.,Dyson, H.J.,Montminy, M.R.,Wright, P.E.; Solution structure of the KIX domain of CBP bound to the transactivation domain of CREB: a model for activator:coactivator interactions.; Cell(Cambridge,Mass.), 91:741-752, 1997; PubMed: 9413984; DOI: 10.1016/S0092-8674(00)80463-8

実験手法

SOLUTION NMR