1JQH

IGF-1 receptor kinase domain

Summary for 1JQH

• Entry DOI: 10.2210/pdb1jqh/pdb
• Related: 1IR3 1IRK
• Descriptor: IGF-1 receptor kinase, MAGNESIUM ION, SULFATE ION, ... (5 entities in total)
• Functional Keywords: protein kinase fold, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Membrane; Single-pass type I membrane protein: P08069
• Total number of polymer chains: 3
• Total formula weight: 107137.70

Authors

Pautsch, A.,Zoephel, A.,Ahorn, H.,Spevak, W.,Hauptmann, R.,Nar, H. (deposition date: 2001-08-07, release date: 2002-04-19, Last modification date: 2021-11-10)

• Primary citation: Pautsch, A.,Zoephel, A.,Ahorn, H.,Spevak, W.,Hauptmann, R.,Nar, H.; Crystal structure of bisphosphorylated IGF-1 receptor kinase: insight into domain movements upon kinase activation.; Structure, 9:955-965, 2001; PubMed: 11591350; DOI: 10.1016/S0969-2126(01)00655-4

Experimental method

X-RAY DIFFRACTION (2.1 Å)