1J49

INSIGHTS INTO DOMAIN CLOSURE, SUBSTRATE SPECIFICITY AND CATALYSIS OF D-LACTATE DEHYDROGENASE FROM LACTOBACILLUS BULGARICUS

1J49 の概要

• エントリーDOI: 10.2210/pdb1j49/pdb
• 分子名称: D-LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: nad-dependent dehydrogenase, last step of glycolysis under anaerobic conditions, reversible interconversion of pyruvate into d-lactate, oxidoreductase
• 由来する生物種: Lactobacillus delbrueckii subsp. bulgaricus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 75665.16

構造登録者

Razeto, A.,Kochhar, S.,Hottinger, H.,Dauter, M.,Wilson, K.S.,Lamzin, V.S. (登録日: 2001-08-14, 公開日: 2002-05-29, 最終更新日: 2023-08-16)

• 主引用文献: Razeto, A.,Kochhar, S.,Hottinger, H.,Dauter, M.,Wilson, K.S.,Lamzin, V.S.; Domain closure, substrate specificity and catalysis of D-lactate dehydrogenase from Lactobacillus bulgaricus.; J.Mol.Biol., 318:109-119, 2002; PubMed: 12054772; DOI: 10.1016/S0022-2836(02)00086-4

実験手法

X-RAY DIFFRACTION (2.2 Å)