1HFD

HUMAN COMPLEMENT FACTOR D IN A P21 CRYSTAL FORM

1HFD の概要

• エントリーDOI: 10.2210/pdb1hfd/pdb
• 分子名称: COMPLEMENT FACTOR D (2 entities in total)
• 機能のキーワード: serine protease, hydrolase, complement, factor d, catalytic triad, self-regulation
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted: P00746
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 24438.81

構造登録者

Jing, H.,Babu, Y.S.,Moore, D.,Kilpatrick, J.M.,Liu, X.-Y.,Volanakis, J.E.,Narayana, S.V.L. (登録日: 1998-06-18, 公開日: 1999-06-22, 最終更新日: 2023-08-09)

• 主引用文献: Jing, H.,Babu, Y.S.,Moore, D.,Kilpatrick, J.M.,Liu, X.Y.,Volanakis, J.E.,Narayana, S.V.; Structures of native and complexed complement factor D: implications of the atypical His57 conformation and self-inhibitory loop in the regulation of specific serine protease activity.; J.Mol.Biol., 282:1061-1081, 1998; PubMed: 9753554; DOI: 10.1006/jmbi.1998.2089

実験手法

X-RAY DIFFRACTION (2.3 Å)