1EEZ
Crystal Structure Determination of HLA-A2.1 Complexed to GP2 Peptide Variant(I2L/V5L)
Summary for 1EEZ
Entry DOI | 10.2210/pdb1eez/pdb |
Related | 1EEY 1QR1 |
Descriptor | HLA-A2.1 MHC CLASS I (HEAVY CHAIN), BETA-2-MICROGLOBULIN (LIGHT CHAIN), GP2 PEPTIDE, ... (4 entities in total) |
Functional Keywords | major histocompatibility complex, peptide binding, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P01892 Secreted: P01884 |
Total number of polymer chains | 6 |
Total formula weight | 89263.40 |
Authors | Sharma, A.K.,Kuhns, J.J.,Collins, E.J. (deposition date: 2000-02-04, release date: 2003-06-10, Last modification date: 2022-12-21) |
Primary citation | Sharma, A.K.,Kuhns, J.J.,Yan, S.,Friedline, R.H.,Long, B.,Tisch, R.,Collins, E.J. Class I major histocompatibility complex anchor substitutions alter the conformation of T cell receptor contacts. J.Biol.Chem., 276:21443-21449, 2001 Cited by PubMed: 11287414DOI: 10.1074/jbc.M010791200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
Download full validation report