1D8T
CRYSTAL STRUCTURE OF ELONGATION FACTOR, TU (EF-TU-MGGDP) COMPLEXED WITH GE2270A, A THIAZOLYL PEPTIDE ANTIBIOTIC
Summary for 1D8T
Entry DOI | 10.2210/pdb1d8t/pdb |
Related | 1E9W 1OLN 2C77 2JQ7 2ZJP 3CF5 |
Related PRD ID | PRD_000225 |
Descriptor | ELONGATION FACTOR TU, THIOCILLIN GE2270, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | hydrolase-antibiotic complex, thiopeptide, antibiotic, antibacterial, thiazole, oxazole, hydrolase, gtpase, translation elongation factor, protein synthesis, nucleotide-binding, phosphorylation, hydrolase/antibiotic |
Biological source | ESCHERICHIA COLI More |
Cellular location | Secreted : Q7M0J8 |
Total number of polymer chains | 4 |
Total formula weight | 92094.23 |
Authors | Heffron, S.E.,Jurnak, F. (deposition date: 1999-10-25, release date: 2000-10-25, Last modification date: 2017-11-01) |
Primary citation | Heffron, S.E.,Jurnak, F. Structure of an EF-TU Complex with a Thiazolyl Peptide Antibiotic Determined at 2.35 A Resolution: Atomic Basis for Ge2270A Inhibition of EF-TU. Biochemistry, 39:37-, 2000 Cited by PubMed: 10625477DOI: 10.1021/BI9913597 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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