1D3D
CRYSTAL STRUCTURE OF HUMAN ALPHA THROMBIN IN COMPLEX WITH BENZOTHIOPHENE INHIBITOR 4
Summary for 1D3D
Entry DOI | 10.2210/pdb1d3d/pdb |
Related | 1D3P 1D3Q 1D3T 1D4P |
Descriptor | ALPHA-THROMBIN, HIRUGEN, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | thrombin; benzo[b]thiophene; blood clotting, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 35319.17 |
Authors | Chirgadze, N.Y. (deposition date: 1999-09-29, release date: 2000-10-04, Last modification date: 2020-07-29) |
Primary citation | Chirgadze, N.Y.,Sall, D.J.,Briggs, S.L.,Clawson, D.K.,Zhang, M.,Smith, G.F.,Schevitz, R.W. The crystal structures of human alpha-thrombin complexed with active site-directed diamino benzo[b]thiophene derivatives: a binding mode for a structurally novel class of inhibitors Protein Sci., 9:29-36, 2000 Cited by PubMed: 10739244PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.04 Å) |
Structure validation
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