1D4P
CRYSTAL STRUCTURE OF HUMAN ALPHA THROMBIN IN COMPLEX WITH 5-AMIDINOINDOLE-4-BENZYLPIPERIDINE INHIBITOR
Summary for 1D4P
Entry DOI | 10.2210/pdb1d4p/pdb |
Related | 1D3D 1D3P 1D3Q 1D3T |
Descriptor | ALPHA-THROMBIN, HIRUGEN, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | thrombin; nonpeptidyl inhibitor; structure-based drug design, blood clotting, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 36052.97 |
Authors | Chirgadze, N.Y. (deposition date: 1999-10-04, release date: 1999-10-20, Last modification date: 2021-04-28) |
Primary citation | Chirgadze, N.Y.,Sall, D.J.,Klimkowski, V.J.,Clawson, D.K.,Briggs, S.L.,Hermann, R.,Smith, G.F.,Gifford-Moore, D.S.,Wery, J.P. The crystal structure of human alpha-thrombin complexed with LY178550, a nonpeptidyl, active site-directed inhibitor. Protein Sci., 6:1412-1417, 1997 Cited by PubMed: 9232642PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.07 Å) |
Structure validation
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