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1D4P

CRYSTAL STRUCTURE OF HUMAN ALPHA THROMBIN IN COMPLEX WITH 5-AMIDINOINDOLE-4-BENZYLPIPERIDINE INHIBITOR

Summary for 1D4P
Entry DOI10.2210/pdb1d4p/pdb
Related1D3D 1D3P 1D3Q 1D3T
DescriptorALPHA-THROMBIN, HIRUGEN, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
Functional Keywordsthrombin; nonpeptidyl inhibitor; structure-based drug design, blood clotting, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
More
Total number of polymer chains3
Total formula weight36052.97
Authors
Chirgadze, N.Y. (deposition date: 1999-10-04, release date: 1999-10-20, Last modification date: 2021-04-28)
Primary citationChirgadze, N.Y.,Sall, D.J.,Klimkowski, V.J.,Clawson, D.K.,Briggs, S.L.,Hermann, R.,Smith, G.F.,Gifford-Moore, D.S.,Wery, J.P.
The crystal structure of human alpha-thrombin complexed with LY178550, a nonpeptidyl, active site-directed inhibitor.
Protein Sci., 6:1412-1417, 1997
Cited by
PubMed: 9232642
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.07 Å)
Structure validation

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