1CSR
Alpha-fluoro acid and alpha-fluoro amide analogs of acetyl-coa as inhibitors of of citrate synthase: effect of pka matching on binding affinity and hydrogen bond length
1CSR の概要
エントリーDOI | 10.2210/pdb1csr/pdb |
分子名称 | CITRATE SYNTHASE, OXALOACETATE ION, ALPHA-FLUORO-AMIDOCARBOXYMETHYLDETHIA COENZYME A COMPLEX, ... (4 entities in total) |
機能のキーワード | oxo-acid-lyase |
由来する生物種 | Gallus gallus (chicken) |
細胞内の位置 | Mitochondrion matrix: P23007 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 49116.51 |
構造登録者 | |
主引用文献 | Schwartz, B.,Drueckhammer, D.G.,Usher, K.C.,Remington, S.J. alpha-Fluoro acid and alpha-fluoro amide analogs of acetyl-CoA as inhibitors of citrate synthase: effect of pKa matching on binding affinity and hydrogen bond length. Biochemistry, 34:15459-15466, 1995 Cited by PubMed: 7492547DOI: 10.1021/bi00047a010 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.7 Å) |
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